TB Module · 7 Sections

Understanding Tuberculosis

An interactive journey through TB — from how it spreads to how it's treated. Explore anatomical diagrams, click hotspots, and test your knowledge.

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What is Tuberculosis?

A bacterial infection that primarily attacks the lungs

Tuberculosis (TB) is caused by a bacterium called Mycobacterium tuberculosis. It mainly affects the lungs, but can also attack other parts of the body like the kidneys, spine, and brain.

TB spreads through the air when an infected person coughs, sneezes, or speaks. It is curable and preventable, yet remains one of the world's deadliest infectious diseases.

10.6 Million
People fell ill with TB globally in 2022
Nigeria #6
Nigeria ranks 6th among the 30 high TB burden countries worldwide
95% Curable
TB can be cured with proper medication taken for 6 months
TRACHEA LEFT LUNG RIGHT LUNG TB Bacteria
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How TB Spreads

Understanding airborne transmission step by step

🤧 INFECTED PERSON AIRBORNE DROPLETS 🙂 NEARBY PERSON
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Infected Person Coughs, Sneezes, or Speaks

When a person with active TB disease coughs, tiny droplets containing TB bacteria are expelled into the air. Even singing or talking can release these droplets.

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Bacteria Travel Through the Air

The droplet nuclei are extremely small (1-5 microns) and can remain suspended in the air for several hours, especially in poorly ventilated spaces.

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Nearby Person Inhales the Bacteria

A susceptible person breathes in the droplet nuclei, which travel deep into the lungs. The bacteria may then establish infection in the lung tissue.

Not from surfaces
TB does NOT spread by shaking hands, sharing food/drinks, touching toilets, or sharing toothbrushes.
Close contact matters
You are most at risk if you spend many hours with an infected person in an enclosed, poorly ventilated room.
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TB in the Lungs

Click on the highlighted areas to learn more

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Bronchi — The Airways
The bronchi are the main air passages leading from the trachea into the lungs. TB bacteria travel down these airways after being inhaled, making their way deeper into the lung tissue.
Alveoli — Air Sacs
The alveoli are tiny air sacs at the end of the airways where oxygen enters the blood. TB bacteria settle in the alveoli and begin to multiply, triggering the immune response.
Granuloma — Walled-off Infection
The immune system tries to contain TB bacteria by forming a granuloma — a hard shell of immune cells around the bacteria. In latent TB, bacteria remain trapped here. If the immune system weakens, bacteria can break free and cause active TB.
Immune Response
Your immune system fights TB by sending white blood cells (macrophages) to surround and contain the bacteria.
Why the Lungs?
TB bacteria are airborne, so they naturally reach the lungs first. The warm, oxygen-rich environment helps them thrive.
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Stages of TB

Understanding the difference between latent and active tuberculosis

Latent TB Infection

Latent TB

The bacteria are in your body but your immune system is keeping them contained. You are not sick and cannot spread TB to others.

  • No symptoms at all
  • Not contagious to others
  • Positive TB skin test or blood test
  • Normal chest X-ray
  • Can develop into active TB if untreated
  • 5-10% lifetime risk of becoming active
Active TB Disease

Active TB

The bacteria have overwhelmed your immune system. You are sick with symptoms and can spread TB to others through the air.

  • 🔴 Persistent cough (3+ weeks)
  • 🔴 Coughing up blood or sputum
  • 🔴 Fever, chills, night sweats
  • 🔴 Unintended weight loss
  • 🔴 Fatigue and weakness
  • 🔴 Contagious — can infect others
Why Treatment Matters for Both Stages
Even latent TB should be treated with preventive therapy to reduce the risk of developing active disease — especially for people with HIV, young children, and those with weakened immune systems.
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Symptoms & Warning Signs

Click on the highlighted areas of the body to learn about each symptom

Tap each glowing circle on the body to reveal symptom details.

Fever & Chills

Persistent low-grade fever, often in the evening, with accompanying chills. The fever may come and go over weeks. Temperature typically ranges from 37.5-38.5°C.

Persistent Cough

A cough that lasts 3 weeks or more is a key warning sign. It may produce sputum (phlegm) and in some cases, blood. The cough worsens over time without treatment.

Unintended Weight Loss

Significant weight loss and decreased appetite are common as the body fights the infection. Patients may lose 5-10kg or more without trying. This is sometimes called "consumption."

Night Sweats

Drenching night sweats that soak through clothing and bedding. These occur as the immune system battles the bacteria during sleep and are a hallmark sign of active TB.

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The Treatment Journey

TB treatment takes 6 months — here's the roadmap to a cure

💊
Diagnosis
Day 1
💉
Intensive Phase
Months 1-2
📈
Continuation
Months 3-6
🎉
Cured!
Month 6

Intensive Phase (Months 1-2)

Four drugs are taken daily: Isoniazid, Rifampicin, Pyrazinamide, and Ethambutol (HRZE). This powerful combination rapidly kills the majority of TB bacteria. Most patients stop being contagious within 2-3 weeks of starting treatment.

Continuation Phase (Months 3-6)

Two drugs continue: Isoniazid and Rifampicin (HR). This phase eliminates remaining bacteria that are slow-growing or dormant. Stopping early risks relapse and drug-resistant TB.

DOT — Directly Observed Therapy
In Nigeria and many countries, a health worker or trained volunteer watches the patient take each dose. This ensures the patient completes the full treatment course and prevents drug resistance. COF supports DOT in communities across Oyo State since 2008.
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Test Your Knowledge

5 questions to check what you've learned about TB

Question 1 of 5
What type of organism causes tuberculosis?
Question 2 of 5
How does TB spread from person to person?
Question 3 of 5
What is the difference between latent TB and active TB?
Question 4 of 5
How long does standard TB treatment take?
Question 5 of 5
What is DOT (Directly Observed Therapy)?
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Score
Keep Learning!
Review the sections above to build your understanding of TB.
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